BDBM50102738 CHEMBL1204162::CHEMBL281799::[2-(1-Benzyl-piperidin-4-yl)-ethyl]-(5H-indeno[1,2-c]pyridazin-3-yl)-amine

SMILES C(CC1CCN(Cc2ccccc2)CC1)Nc1cc2Cc3ccccc3-c2nn1

InChI Key InChIKey=INIMHDIZIDCHML-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50102738   

TargetAcetylcholinesterase(Electric eel)
Prestwick Chemical

Curated by ChEMBL
LigandPNGBDBM50102738(CHEMBL1204162 | CHEMBL281799 | [2-(1-Benzyl-piperi...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration towards acetylcholinesterase in electric eelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Louis Pasteur University

Curated by ChEMBL
LigandPNGBDBM50102738(CHEMBL1204162 | CHEMBL281799 | [2-(1-Benzyl-piperi...)
Affinity DataIC50: 230nMAssay Description:Inhibition of butyrylcholinesterase from human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Louis Pasteur University

Curated by ChEMBL
LigandPNGBDBM50102738(CHEMBL1204162 | CHEMBL281799 | [2-(1-Benzyl-piperi...)
Affinity DataIC50: 74nMAssay Description:In vitro inhibition of acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Prestwick Chemical

Curated by ChEMBL
LigandPNGBDBM50102738(CHEMBL1204162 | CHEMBL281799 | [2-(1-Benzyl-piperi...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of electric eel acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50102738(CHEMBL1204162 | CHEMBL281799 | [2-(1-Benzyl-piperi...)
Affinity DataIC50: 10nMAssay Description:Inhibition of AChE in rat cerebral cortex homogenates using acetylthiocholine iodide as substrate after 8 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed