BDBM50102683 CHEMBL313228::N-{(4S)-4-amino-5-[(3-aminopropyl)amino]pentyl}-N'-nitroguanidine

SMILES NCCCNC[C@@H](N)CCCNC(=N)N[N+]([O-])=O

InChI Key InChIKey=URNXGQJFPYGXFA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102683   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50102683(N-{(4S)-4-amino-5-[(3-aminopropyl)amino]pentyl}-N'...)
Affinity DataKi:  290nMAssay Description:Inhibitory activity against recombinant rat nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50102683(N-{(4S)-4-amino-5-[(3-aminopropyl)amino]pentyl}-N'...)
Affinity DataKi:  460nMAssay Description:Inhibitory activity against neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50102683(N-{(4S)-4-amino-5-[(3-aminopropyl)amino]pentyl}-N'...)
Affinity DataKi:  7.30E+4nMAssay Description:Inhibitory activity against recombinant murine iNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50102683(N-{(4S)-4-amino-5-[(3-aminopropyl)amino]pentyl}-N'...)
Affinity DataKi:  5.24E+5nMAssay Description:Inhibitory activity against recombinant bovine eNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50102683(N-{(4S)-4-amino-5-[(3-aminopropyl)amino]pentyl}-N'...)
Affinity DataKi:  4.11E+5nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50102683(N-{(4S)-4-amino-5-[(3-aminopropyl)amino]pentyl}-N'...)
Affinity DataKi:  1.23E+5nMAssay Description:Inhibitory activity against Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed