BDBM50102520 2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(naphth-1-ylmethyl)triazen-1-yl]-4-chlorophenyl}-6-ethylpyrimidine::CHEMBL313553

SMILES CCc1nc(N)nc(N)c1-c1ccc(Cl)c(c1)\N=N\N(CCOC(C)=O)Cc1cccc2ccccc12

InChI Key InChIKey=XUHIHEJRUJFQPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50102520   

TargetDihydrofolate reductase(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102520(2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(naphth-...)
Affinity DataIC50: 280nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102520(2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(naphth-...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed