BDBM50102508 2,4-Diamino-5-{3-[3-benzyl-3-(3-hydroxypropoyl)(triazen-1-yl]-4-chlorophenyl}-6-ethylpyrimidine::CHEMBL86085

SMILES CCc1nc(N)nc(N)c1-c1ccc(Cl)c(c1)\N=N\N(CCCO)Cc1ccccc1

InChI Key InChIKey=RIURYJFICKLHHI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50102508   

TargetDihydrofolate reductase(Mycobacterium avium)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102508(2,4-Diamino-5-{3-[3-benzyl-3-(3-hydroxypropoyl)(tr...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in Mycobacterium aviumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102508(2,4-Diamino-5-{3-[3-benzyl-3-(3-hydroxypropoyl)(tr...)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102508(2,4-Diamino-5-{3-[3-benzyl-3-(3-hydroxypropoyl)(tr...)
Affinity DataIC50: 7.35E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed