BDBM50102500 2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(4-fluoro benzyl)triazen-1-yl]-4-chlorophenyl}-6-ethylpyrimidine::CHEMBL87549

SMILES CCc1nc(N)nc(N)c1-c1ccc(Cl)c(c1)\N=N\N(CCOC(C)=O)Cc1ccc(F)cc1

InChI Key InChIKey=RNAPBKRIXYBLAL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50102500   

TargetDihydrofolate reductase(Mycobacterium avium)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102500(2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(4-fluor...)
Affinity DataIC50: 7.46E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in Mycobacterium aviumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102500(2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(4-fluor...)
Affinity DataIC50: 3.83E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102500(2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(4-fluor...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed