BDBM50102473 (4'-methoxy-biphenyl-4-sulfonylamino)-[1-(morpholine-4-carbonyl)-piperidin-4-yl]-acetic acid::CHEMBL83282

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NC(C1CCN(CC1)C(=O)N1CCOCC1)C(O)=O

InChI Key InChIKey=ICFOTHUAZLHTNP-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50102473   

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102473((4'-methoxy-biphenyl-4-sulfonylamino)-[1-(morpholi...)
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50102473((4'-methoxy-biphenyl-4-sulfonylamino)-[1-(morpholi...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50102473((4'-methoxy-biphenyl-4-sulfonylamino)-[1-(morpholi...)
Affinity DataIC50: 1.80nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102473((4'-methoxy-biphenyl-4-sulfonylamino)-[1-(morpholi...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102473((4'-methoxy-biphenyl-4-sulfonylamino)-[1-(morpholi...)
Affinity DataIC50: 3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102473((4'-methoxy-biphenyl-4-sulfonylamino)-[1-(morpholi...)
Affinity DataIC50: 50.8nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102473((4'-methoxy-biphenyl-4-sulfonylamino)-[1-(morpholi...)
Affinity DataIC50: 221nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102473((4'-methoxy-biphenyl-4-sulfonylamino)-[1-(morpholi...)
Affinity DataIC50: 1.76E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102473((4'-methoxy-biphenyl-4-sulfonylamino)-[1-(morpholi...)
Affinity DataIC50: 8.57E+3nMAssay Description:Inhibitory activity against matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed