BDBM50102446 Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(EtCbm)]-D-[Aph(EtCbm)]-Leu-ILys-Pro-DAla-NH2::CHEMBL268875

SMILES CCNC(=O)Nc1ccc(C[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](Cc2cccnc2)NC(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(C)=O)C(=O)N[C@H](Cc2ccc(NC(=O)NCC)cc2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@H](C)C(N)=O)cc1

InChI Key InChIKey=CQNFYZQMLPNPAY-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50102446   

TargetGonadotropin-releasing hormone receptor(Human)
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102446(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(EtCbm)]-D-[Ap...)
Affinity DataIC50: 5nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102446(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(EtCbm)]-D-[Ap...)
Affinity DataKd:  1.26nMAssay Description:Competitive antagonism of GnRH-induced response in the reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed