BDBM50102428 CHEMBL137829::N-[2-(4-Chloro-phenyl)-ethyl]-5-(2,5-dihydroxy-benzylamino)-2-hydroxy-benzamide

SMILES Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)NCCc2ccc(Cl)cc2)c1

InChI Key InChIKey=KQUODGYCTPWEAV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50102428   

TargetTyrosine-protein kinase SYK(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102428(N-[2-(4-Chloro-phenyl)-ethyl]-5-(2,5-dihydroxy-ben...)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of Syk protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102428(N-[2-(4-Chloro-phenyl)-ethyl]-5-(2,5-dihydroxy-ben...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of epidermal growth factor receptor phosphorylation in BaF3 mouse lymphoid cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-2B chain(Bovine)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102428(N-[2-(4-Chloro-phenyl)-ethyl]-5-(2,5-dihydroxy-ben...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed