BDBM50102416 5-(2,5-Dihydroxy-benzylamino)-N-[2-(4-fluoro-phenyl)-ethyl]-2-hydroxy-benzamide::CHEMBL44918

SMILES Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)NCCc2ccc(F)cc2)c1

InChI Key InChIKey=LNLPBDFBYNOLAV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102416   

TargetTubulin beta-2B chain(Bovine)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102416(5-(2,5-Dihydroxy-benzylamino)-N-[2-(4-fluoro-pheny...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102416(5-(2,5-Dihydroxy-benzylamino)-N-[2-(4-fluoro-pheny...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition of Syk protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102416(5-(2,5-Dihydroxy-benzylamino)-N-[2-(4-fluoro-pheny...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of epidermal growth factor receptor phosphorylation in BaF3 mouse lymphoid cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bovine)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102416(5-(2,5-Dihydroxy-benzylamino)-N-[2-(4-fluoro-pheny...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed