BDBM50102387 1-Phenyl-3-(4-pyrimidin-2-yl-piperazin-1-yl)-propan-1-ol::1-phenyl-3-(4-(pyrimidin-2-yl)piperazin-1-yl)propan-1-ol::CHEMBL135712

SMILES OC(CCN1CCN(CC1)c1ncccn1)c1ccccc1

InChI Key InChIKey=GNEPRYRWYXNGOT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50102387   

Target5-hydroxytryptamine receptor 1A(Human)
Universidade Federal Da Para£Ba

Curated by ChEMBL
LigandPNGBDBM50102387(1-phenyl-3-(4-(pyrimidin-2-yl)piperazin-1-yl)propa...)
Affinity DataKi:  372nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102387(1-phenyl-3-(4-(pyrimidin-2-yl)piperazin-1-yl)propa...)
Affinity DataKi:  375nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102387(1-phenyl-3-(4-(pyrimidin-2-yl)piperazin-1-yl)propa...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]paroxetineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed