BDBM50102386 1-(2,5-Dimethyl-thiophen-3-yl)-3-[4-(4-fluoro-2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one::1-(2,5-dimethylthiophen-3-yl)-3-(4-(4-fluoro-2-methoxyphenyl)piperazin-1-yl)propan-1-one::CHEMBL341381

SMILES COc1cc(F)ccc1N1CCN(CCC(=O)c2cc(C)sc2C)CC1

InChI Key InChIKey=GHCHMYSZZHTHJD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50102386   

Target5-hydroxytryptamine receptor 1A(Human)
Universidade Federal Da Para£Ba

Curated by ChEMBL
LigandPNGBDBM50102386(1-(2,5-dimethylthiophen-3-yl)-3-(4-(4-fluoro-2-met...)
Affinity DataKi:  12.9nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102386(1-(2,5-dimethylthiophen-3-yl)-3-(4-(4-fluoro-2-met...)
Affinity DataKi:  13nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102386(1-(2,5-dimethylthiophen-3-yl)-3-(4-(4-fluoro-2-met...)
Affinity DataKi:  750nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]paroxetineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed