BDBM50102373 3-(4-(naphthalen-1-yl)piperazin-1-yl)-1-(thiophen-3-yl)propan-1-one::3-(4-Naphthalen-1-yl-piperazin-1-yl)-1-thiophen-3-yl-propan-1-one::CHEMBL135295

SMILES O=C(CCN1CCN(CC1)c1cccc2ccccc12)c1ccsc1

InChI Key InChIKey=AEEDQVJYSPEPSO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102373   

Target5-hydroxytryptamine receptor 1A(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102373(3-(4-Naphthalen-1-yl-piperazin-1-yl)-1-thiophen-3-...)
Affinity DataKi:  34.7nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102373(3-(4-Naphthalen-1-yl-piperazin-1-yl)-1-thiophen-3-...)
Affinity DataKi:  34.7nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102373(3-(4-Naphthalen-1-yl-piperazin-1-yl)-1-thiophen-3-...)
Affinity DataKi:  35nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102373(3-(4-Naphthalen-1-yl-piperazin-1-yl)-1-thiophen-3-...)
Affinity DataKi:  800nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]paroxetineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed