BDBM50102368 1-(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)-4-(pyridin-2-yl)piperazine::1-[3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL133139

SMILES FC(F)(F)c1ccc(OC(CCN2CCN(CC2)c2ccccn2)c2ccccc2)cc1

InChI Key InChIKey=BFUZKYZYAVZLHQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102368   

TargetSodium-dependent serotonin transporter(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102368(1-[3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]paroxetineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102368(1-[3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-...)
Affinity DataKi:  1.58E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102368(1-[3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-...)
Affinity DataKi:  1.58E+3nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102368(1-[3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-...)
Affinity DataKi:  1.60E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed