BDBM50102361 3-(4-(2-chlorophenyl)piperazin-1-yl)-1-(thiophen-3-yl)propan-1-ol::3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-1-thiophen-3-yl-propan-1-ol::CHEMBL135753

SMILES OC(CCN1CCN(CC1)c1ccccc1Cl)c1ccsc1

InChI Key InChIKey=PXJRWPJLTNUQTJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102361   

Target5-hydroxytryptamine receptor 1A(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102361(3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-1-thiophen-...)
Affinity DataKi:  200nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102361(3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-1-thiophen-...)
Affinity DataKi:  200nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102361(3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-1-thiophen-...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]paroxetineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102361(3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-1-thiophen-...)
Affinity DataKi:  5.01E+3nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed