BDBM50102346 1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-thiophen-3-yl-propyl]-piperazine::1-(2-methoxyphenyl)-4-(3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propyl)piperazine::CHEMBL134743

SMILES COc1ccccc1N1CCN(CCC(Oc2cccc3ccccc23)c2ccsc2)CC1

InChI Key InChIKey=FCNUZSYKUANYNY-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50102346   

TargetSodium-dependent serotonin transporter(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102346(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
Affinity DataKi:  150nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]paroxetineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102346(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
Affinity DataKi:  180nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidade Federal Da Para£Ba

Curated by ChEMBL
LigandPNGBDBM50102346(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
Affinity DataKi:  182nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102346(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
Affinity DataKi:  1.25E+3nMAssay Description:Affinity at 5-hydroxytryptamine 1D receptor from calf caudate using [3H]5-HT as radioligand (For sumatriptan = Ki(nM)-12+/-1.9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102346(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
Affinity DataKi:  2.50E+3nMAssay Description:Affinity at dopamine D2 receptor from rat striatum using [3H]spiroperidol as radioligand (For haloperidol Ki(nM)= 1.5+/-1.2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102346(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
Affinity DataKi: >5.00E+3nMAssay Description:Affinity at 5-hydroxytryptamine 2 receptor from rat frontal cortex using [3H]ketanserin as radioligand (For ketanserin = Ki(nM)=0.7+/-0.09)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102346(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
Affinity DataKi: >5.00E+3nMAssay Description:Affinity at 5-hydroxytryptamine 3 receptor from rat frontal cortex using [3H]granisetron as radioligand (For granisetron = Ki(nM)=0.3+/-0.01)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed