BDBM50102345 1-(2,5-Dimethyl-thiophen-3-yl)-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one oxime::CHEMBL135918::CHEMBL335925

SMILES COc1ccccc1N1CCN(CCC(N=O)c2cc(C)sc2C)CC1

InChI Key InChIKey=NFQFFAWDWCIADK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102345   

Target5-hydroxytryptamine receptor 1A(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102345(CHEMBL335925 | CHEMBL135918 | 1-(2,5-Dimethyl-thio...)
Affinity DataKi:  85nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102345(CHEMBL335925 | CHEMBL135918 | 1-(2,5-Dimethyl-thio...)
Affinity DataKi:  130nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102345(CHEMBL335925 | CHEMBL135918 | 1-(2,5-Dimethyl-thio...)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]paroxetineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102345(CHEMBL335925 | CHEMBL135918 | 1-(2,5-Dimethyl-thio...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]paroxetineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed