BDBM50102342 2-(4-(3-(2,5-dimethylthiophen-3-yl)-3-hydroxypropyl)piperazin-1-yl)phenol::2-{4-[3-(2,5-Dimethyl-thiophen-3-yl)-3-hydroxy-propyl]-piperazin-1-yl}-phenol::CHEMBL133207

SMILES Cc1cc(C(O)CCN2CCN(CC2)c2ccccc2O)c(C)s1

InChI Key InChIKey=ILEHGFRGCDSQNV-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102342   

Target5-hydroxytryptamine receptor 1A(Human)
Universidade Federal Da Para£Ba

Curated by ChEMBL
LigandPNGBDBM50102342(2-(4-(3-(2,5-dimethylthiophen-3-yl)-3-hydroxypropy...)
Affinity DataKi:  89.1nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102342(2-(4-(3-(2,5-dimethylthiophen-3-yl)-3-hydroxypropy...)
Affinity DataKi:  90nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidade Federal Da Para£Ba

Curated by ChEMBL
LigandPNGBDBM50102342(2-(4-(3-(2,5-dimethylthiophen-3-yl)-3-hydroxypropy...)
Affinity DataKi:  91.2nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102342(2-(4-(3-(2,5-dimethylthiophen-3-yl)-3-hydroxypropy...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]paroxetineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed