BDBM50102307 3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidine::CHEMBL421259

SMILES Cc1cc(C)n2nc(c(-c3ccc(F)cc3)c2n1)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=ZPIGMVKWDIWIQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50102307   

TargetProstaglandin G/H synthase 1(Human)
J. Uriach & CíA.

Curated by ChEMBL
LigandPNGBDBM50102307(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in U-937 cells from human histiocytic lymphomaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
J. Uriach & CíA.

Curated by ChEMBL
LigandPNGBDBM50102307(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 154nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed