BDBM50102246 CHEMBL59590::N-[3-(4-Cyano-4-o-tolyl-piperidin-1-yl)-propyl]-2-hydroxy-2,2-di-p-tolyl-acetamide

SMILES Cc1ccc(cc1)C(O)(C(=O)NCCCN1CCC(CC1)(C#N)c1ccccc1C)c1ccc(C)cc1

InChI Key InChIKey=FJFCVNFWRHPKPL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50102246   

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50102246(N-[3-(4-Cyano-4-o-tolyl-piperidin-1-yl)-propyl]-2-...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity towards cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50102246(N-[3-(4-Cyano-4-o-tolyl-piperidin-1-yl)-propyl]-2-...)
Affinity DataKi:  570nMAssay Description:In vitro binding affinity towards cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50102246(N-[3-(4-Cyano-4-o-tolyl-piperidin-1-yl)-propyl]-2-...)
Affinity DataKi:  1.50E+3nMAssay Description:In vitro binding affinity towards cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed