BDBM50102094 (3-Chloro-4-fluoro-phenyl)-[6-(2-imidazol-1-yl-ethoxy)-7-methoxy-quinazolin-4-yl]-amine::CHEMBL294034

SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCn1ccnc1

InChI Key InChIKey=XXBDUYQPZRPNMB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50102094   

TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102094((3-Chloro-4-fluoro-phenyl)-[6-(2-imidazol-1-yl-eth...)
Affinity DataIC50: 66nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102094((3-Chloro-4-fluoro-phenyl)-[6-(2-imidazol-1-yl-eth...)
Affinity DataIC50: 60nMAssay Description:Inhibition of EGFR (unknown origin) using biotinylated-PTP1B (Tyr66) as substrate incubated for 5 mins prior to substrate addition measured after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed