BDBM50101878 3-Benzyl-2-(3-bromo-2-hydroxy-5-methyl-phenyl)-1H-indole-5-carboxamidine::CHEMBL50933

SMILES Cc1cc(Br)c(O)c(c1)-c1[nH]c2ccc(cc2c1Cc1ccccc1)C(N)=N

InChI Key InChIKey=PTXZAYDCYHSSEH-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50101878   

TargetCoagulation factor X(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101878(3-Benzyl-2-(3-bromo-2-hydroxy-5-methyl-phenyl)-1H-...)
Affinity DataKi:  20nMAssay Description:Inhibitory activity against Coagulation factor X in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101878(3-Benzyl-2-(3-bromo-2-hydroxy-5-methyl-phenyl)-1H-...)
Affinity DataKi:  260nMAssay Description:Inhibitory activity against thrombin(fIIa) in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101878(3-Benzyl-2-(3-bromo-2-hydroxy-5-methyl-phenyl)-1H-...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory activity against urokinase-type plasminogen activator (microPa) in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101878(3-Benzyl-2-(3-bromo-2-hydroxy-5-methyl-phenyl)-1H-...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against trypsin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101878(3-Benzyl-2-(3-bromo-2-hydroxy-5-methyl-phenyl)-1H-...)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibitory activity against plasmin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed