BDBM50101802 CHEMBL3398175

SMILES COc1ccccc1-c1ccc2cnc(Nc3ccc(cc3OC)[C@H]3CCN(CCO)C[C@@H]3O)nn12

InChI Key InChIKey=UVPQQVIBGBMPDZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50101802   

TargetALK tyrosine kinase receptor(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50101802(CHEMBL3398175)
Affinity DataIC50: 5nMAssay Description:Inhibition of ALK (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50101802(CHEMBL3398175)
Affinity DataIC50: 50nMAssay Description:Inhibition of ALK (unknown origin) by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50101802(CHEMBL3398175)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human ERG by patch clamp cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50101802(CHEMBL3398175)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50101802(CHEMBL3398175)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50101802(CHEMBL3398175)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50101802(CHEMBL3398175)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50101802(CHEMBL3398175)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2016
Entry Details Article
PubMed