BDBM50101645 (2,4-Diamino-5-methyl-pyrido[2,3-d]pyrimidin-6-yl)-methanol::CHEMBL311432

SMILES Cc1c(CO)cnc2nc(N)nc(N)c12

InChI Key InChIKey=YYQGALGCAWKAKY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101645   

TargetDihydrofolate reductase(Pneumocystis carinii)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101645((2,4-Diamino-5-methyl-pyrido[2,3-d]pyrimidin-6-yl)...)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibitory concentration against dihydrofolate reductase dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101645((2,4-Diamino-5-methyl-pyrido[2,3-d]pyrimidin-6-yl)...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101645((2,4-Diamino-5-methyl-pyrido[2,3-d]pyrimidin-6-yl)...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed