BDBM50101644 3-(2,4-Diamino-quinazolin-6-yl)-acrylic acid phenyl ester::CHEMBL80123

SMILES Nc1nc(N)c2cc(\C=C\C(=O)Oc3ccccc3)ccc2n1

InChI Key InChIKey=DGAFGQKBZPRSOB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101644   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101644(3-(2,4-Diamino-quinazolin-6-yl)-acrylic acid pheny...)
Affinity DataIC50: 189nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101644(3-(2,4-Diamino-quinazolin-6-yl)-acrylic acid pheny...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory concentration against dihydrofolate reductase dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101644(3-(2,4-Diamino-quinazolin-6-yl)-acrylic acid pheny...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed