BDBM50101643 6-[(Methyl-phenyl-amino)-methyl]-quinazoline-2,4-diamine::CHEMBL78578

SMILES CN(Cc1ccc2nc(N)nc(N)c2c1)c1ccccc1

InChI Key InChIKey=UPIGGXVTJQLGAV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101643   

TargetDihydrofolate reductase(Pneumocystis carinii)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101643(6-[(Methyl-phenyl-amino)-methyl]-quinazoline-2,4-d...)
Affinity DataIC50: 96nMAssay Description:Inhibitory concentration against dihydrofolate reductase dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101643(6-[(Methyl-phenyl-amino)-methyl]-quinazoline-2,4-d...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101643(6-[(Methyl-phenyl-amino)-methyl]-quinazoline-2,4-d...)
Affinity DataIC50: 69nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101643(6-[(Methyl-phenyl-amino)-methyl]-quinazoline-2,4-d...)
Affinity DataIC50: 69nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed