BDBM50101639 2,3,4-Trimethoxy-benzoic acid 2,4-diamino-quinazolin-6-ylmethyl ester::CHEMBL309792

SMILES COc1ccc(C(=O)OCc2ccc3nc(N)nc(N)c3c2)c(OC)c1OC

InChI Key InChIKey=NOYMHRHEOMACPO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101639   

TargetDihydrofolate reductase(Pneumocystis carinii)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101639(2,3,4-Trimethoxy-benzoic acid 2,4-diamino-quinazol...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory concentration against dihydrofolate reductase dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101639(2,3,4-Trimethoxy-benzoic acid 2,4-diamino-quinazol...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101639(2,3,4-Trimethoxy-benzoic acid 2,4-diamino-quinazol...)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed