BDBM50101636 2,5-Dimethoxy-benzoic acid 2,4-diamino-quinazolin-6-ylmethyl ester::CHEMBL79216

SMILES COc1ccc(OC)c(c1)C(=O)OCc1ccc2nc(N)nc(N)c2c1

InChI Key InChIKey=AVJYQOKXESFSHO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101636   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101636(2,5-Dimethoxy-benzoic acid 2,4-diamino-quinazolin-...)
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101636(2,5-Dimethoxy-benzoic acid 2,4-diamino-quinazolin-...)
Affinity DataIC50: 420nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101636(2,5-Dimethoxy-benzoic acid 2,4-diamino-quinazolin-...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory concentration against dihydrofolate reductase dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed