BDBM50101633 3,4,5-Trimethoxy-benzoic acid 2,4-diamino-quinazolin-6-ylmethyl ester::CHEMBL78022

SMILES COc1cc(cc(OC)c1OC)C(=O)OCc1ccc2nc(N)nc(N)c2c1

InChI Key InChIKey=BAGKYHYPCLBURO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101633   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101633(3,4,5-Trimethoxy-benzoic acid 2,4-diamino-quinazol...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101633(3,4,5-Trimethoxy-benzoic acid 2,4-diamino-quinazol...)
Affinity DataIC50: 26nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50101633(3,4,5-Trimethoxy-benzoic acid 2,4-diamino-quinazol...)
Affinity DataIC50: 560nMAssay Description:Inhibitory concentration against dihydrofolate reductase dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed