BDBM50101609 1-{2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinolin-3-ylmethyl}-3-phenyl-thiourea::CHEMBL75802

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1CNC(=S)Nc1ccccc1

InChI Key InChIKey=DDDVGFDKIJEQJS-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101609   

TargetDelta-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101609(1-{2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-pr...)
Affinity DataIC50: 0.270nMAssay Description:Binding affinity at cloned human delta-opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101609(1-{2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-pr...)
Affinity DataEC50:  1.70nMAssay Description:Agonist potency using GTP-gamma [35S]- binding assay for delta-opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101609(1-{2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-pr...)
Affinity DataIC50: 5.40nMAssay Description:Agonist potency using GTP-gamma [35S]- binding assay for mu-opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50101609(1-{2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-pr...)
Affinity DataIC50: 51nMAssay Description:Agonist potency using GTP-gamma [35S]- binding assay for opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed