BDBM50101536 1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(4-phenoxy-phenyl)-urea::CHEMBL419086

SMILES C[C@H]([C@H](O)c1ccccc1)N(C)C(=O)Nc1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=QGKGFNHGECNPEI-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101536   

TargetNeuropeptide Y receptor type 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50101536(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y2 Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50101536(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)
Affinity DataIC50: 45nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50101536(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y1 Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50101536(1-(2-Hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-3-(...)
Affinity DataKi:  477nMAssay Description:Tested in a cellular assay measuring forskolin-induced cyclic AMP accumulation in 293 cells transfected with the human NPY5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed