BDBM50101528 (R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4*-hydroxy-2-(4-phenyl-butyl)-succinamide::CHEMBL73803::N*1*-(2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4*-hydroxy-2-(4-phenyl-butyl)-succinamide

SMILES ONC(=O)C[C@@H](CCCCc1ccccc1)C(=O)N[C@@H](CC1CCCCC1)C(=O)NCCc1ccccc1

InChI Key InChIKey=ZWZXXDZMSDNWNF-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50101528   

Target72 kDa type IV collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101528(N*1*-(2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4...)
Affinity DataKi:  0.254nMAssay Description:Inhibitory constant against matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101528(N*1*-(2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4...)
Affinity DataKi:  0.254nMAssay Description:Inhibition of the gelatinase-A enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetStromelysin-1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101528(N*1*-(2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4...)
Affinity DataKi:  177nMAssay Description:Inhibitory constant against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101528(N*1*-(2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4...)
Affinity DataKi:  177nMAssay Description:Inhibition of the stromelysin enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101528(N*1*-(2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibitory constant against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101528(N*1*-(2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of the collagenase enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article