BDBM50101521 (R)-3-{(S)-2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-ethylcarbamoyl}-6-(4-methoxy-phenyl)-hexanoic acid::3-{2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-ethylcarbamoyl}-6-(4-methoxy-phenyl)-hexanoic acid::CHEMBL309067

SMILES COc1ccc(CCC[C@H](CC(O)=O)C(=O)N[C@@H](CC2CCCCC2)C(=O)NCCc2ccc(cc2)S(N)(=O)=O)cc1

InChI Key InChIKey=JWBVNSRNJDQUGY-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50101521   

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101521(3-{2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcar...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of the Gelatinase-A enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101521(3-{2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcar...)
Affinity DataKi:  1.83nMAssay Description:Inhibitory constant against matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101521(3-{2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcar...)
Affinity DataKi:  1.11E+3nMAssay Description:Inhibitory constant against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101521(3-{2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcar...)
Affinity DataKi:  1.11E+3nMAssay Description:Inhibition of the Stromelysin enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101521(3-{2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcar...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of the Collagenase enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101521(3-{2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcar...)
Affinity DataKi:  1.00E+5nMAssay Description:Inhibitory constant against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101521(3-{2-Cyclohexyl-1-[2-(4-sulfamoyl-phenyl)-ethylcar...)
Affinity DataKi:  1.00E+5nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed