BDBM50101502 3-[(S)-3-Cyclohexyl-2-((S)-5-phenyl-2-phosphonomethyl-pentanoylamino)-propionylamino]-propionic acid::3-[3-Cyclohexyl-2-(5-phenyl-2-phosphonomethyl-pentanoylamino)-propionylamino]-propionic acid::CHEMBL307211

SMILES OC(=O)CCNC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CCCc1ccccc1)CP(O)(O)=O

InChI Key InChIKey=WFOYCJYFLJCILB-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50101502   

Target72 kDa type IV collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101502(3-[(S)-3-Cyclohexyl-2-((S)-5-phenyl-2-phosphonomet...)
Affinity DataKi:  46.5nMAssay Description:Inhibitory constant against matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101502(3-[(S)-3-Cyclohexyl-2-((S)-5-phenyl-2-phosphonomet...)
Affinity DataKi:  47nMAssay Description:Inhibition of the Gelatinase-A enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetStromelysin-1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101502(3-[(S)-3-Cyclohexyl-2-((S)-5-phenyl-2-phosphonomet...)
Affinity DataKi:  952nMAssay Description:Inhibitory constant against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101502(3-[(S)-3-Cyclohexyl-2-((S)-5-phenyl-2-phosphonomet...)
Affinity DataKi:  952nMAssay Description:Inhibition of the Stromelysin enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101502(3-[(S)-3-Cyclohexyl-2-((S)-5-phenyl-2-phosphonomet...)
Affinity DataKi:  2.21E+4nMAssay Description:Inhibitory constant against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101502(3-[(S)-3-Cyclohexyl-2-((S)-5-phenyl-2-phosphonomet...)
Affinity DataKi:  2.21E+4nMAssay Description:Inhibition of the Collagenase enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article