BDBM50101500 (R)-3-(((S)-3-cyclohexyl-1-(4-morpholinobutylamino)-1-oxopropan-2-yl)carbamoyl)-6-p-tolylhexanoic acid::(R)-3-[(S)-2-Cyclohexyl-1-(4-morpholin-4-yl-butylcarbamoyl)-ethylcarbamoyl]-6-p-tolyl-hexanoic acid::3-[2-Cyclohexyl-1-(4-morpholin-4-yl-butylcarbamoyl)-ethylcarbamoyl]-6-p-tolyl-hexanoic acid::CHEMBL307027

SMILES Cc1ccc(CCC[C@H](CC(O)=O)C(=O)N[C@@H](CC2CCCCC2)C(=O)NCCCCN2CCOCC2)cc1

InChI Key InChIKey=RGTVFBJQARSWHO-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50101500   

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101500((R)-3-[(S)-2-Cyclohexyl-1-(4-morpholin-4-yl-butylc...)
Affinity DataKi:  10nMAssay Description:Inhibition of the Gelatinase-A enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101500((R)-3-[(S)-2-Cyclohexyl-1-(4-morpholin-4-yl-butylc...)
Affinity DataKi:  10.3nMAssay Description:Inhibitory constant against matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101500((R)-3-[(S)-2-Cyclohexyl-1-(4-morpholin-4-yl-butylc...)
Affinity DataKi:  358nMAssay Description:Inhibition of the Stromelysin enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101500((R)-3-[(S)-2-Cyclohexyl-1-(4-morpholin-4-yl-butylc...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory constant against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101500((R)-3-[(S)-2-Cyclohexyl-1-(4-morpholin-4-yl-butylc...)
Affinity DataKi:  5.50E+4nMAssay Description:Inhibition of the Collagenase enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101500((R)-3-[(S)-2-Cyclohexyl-1-(4-morpholin-4-yl-butylc...)
Affinity DataKi:  1.00E+5nMAssay Description:Inhibitory constant against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101500((R)-3-[(S)-2-Cyclohexyl-1-(4-morpholin-4-yl-butylc...)
Affinity DataKi:  1.00E+5nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed