BDBM50101498 CHEMBL74977::[(S)-2-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethylcarbamoyl)-5-phenyl-pentyl]-phosphonic acid::[2-(2-Cyclohexyl-1-phenethylcarbamoyl-ethylcarbamoyl)-5-phenyl-pentyl]-phosphonic acid

SMILES OP(O)(=O)C[C@@H](CCCc1ccccc1)C(=O)N[C@@H](CC1CCCCC1)C(=O)NCCc1ccccc1

InChI Key InChIKey=OXBBHJALLZTSBF-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50101498   

Target72 kDa type IV collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101498([(S)-2-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethy...)
Affinity DataKi:  18.9nMAssay Description:Inhibitory constant against matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101498([(S)-2-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethy...)
Affinity DataKi:  19nMAssay Description:Inhibition of the Gelatinase-A enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetStromelysin-1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101498([(S)-2-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethy...)
Affinity DataKi:  701nMAssay Description:Inhibitory constant against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101498([(S)-2-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethy...)
Affinity DataKi:  701nMAssay Description:Inhibition of the Stromelysin enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101498([(S)-2-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethy...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibitory constant against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101498([(S)-2-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethy...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of the Collagenase enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article