BDBM50101493 CHEMBL306779::{(S)-2-[(S)-2-Cyclohexyl-1-(2-morpholin-4-yl-ethylcarbamoyl)-ethylcarbamoyl]-5-phenyl-pentyl}-phosphonic acid::{2-[2-Cyclohexyl-1-(2-morpholin-4-yl-ethylcarbamoyl)-ethylcarbamoyl]-5-phenyl-pentyl}-phosphonic acid

SMILES OP(O)(=O)C[C@@H](CCCc1ccccc1)C(=O)N[C@@H](CC1CCCCC1)C(=O)NCCN1CCOCC1

InChI Key InChIKey=PENUYKDCGZXPRG-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50101493   

Target72 kDa type IV collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101493({(S)-2-[(S)-2-Cyclohexyl-1-(2-morpholin-4-yl-ethyl...)
Affinity DataKi:  812nMAssay Description:Inhibitory constant against matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101493({(S)-2-[(S)-2-Cyclohexyl-1-(2-morpholin-4-yl-ethyl...)
Affinity DataKi:  812nMAssay Description:Inhibition of the Gelatinase-A enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetStromelysin-1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101493({(S)-2-[(S)-2-Cyclohexyl-1-(2-morpholin-4-yl-ethyl...)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibitory constant against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101493({(S)-2-[(S)-2-Cyclohexyl-1-(2-morpholin-4-yl-ethyl...)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of the Stromelysin enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101493({(S)-2-[(S)-2-Cyclohexyl-1-(2-morpholin-4-yl-ethyl...)
Affinity DataKi:  1.00E+5nMAssay Description:Inhibitory constant against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101493({(S)-2-[(S)-2-Cyclohexyl-1-(2-morpholin-4-yl-ethyl...)
Affinity DataKi:  1.00E+5nMAssay Description:Inhibition of the Collagenase enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article