BDBM50101416 CHEMBL307488::[(R)-2-(3H-Indol-3-yl)-1-methyl-1-((S)-1-phenyl-ethylcarbamoyl)-ethyl]-carbamic acid benzofuran-2-ylmethyl ester::[2-(1H-Indol-3-yl)-1-methyl-1-(1-phenyl-ethylcarbamoyl)-ethyl]-carbamic acid benzofuran-2-ylmethyl ester

SMILES C[C@H](NC(=O)[C@@](C)(Cc1c[nH]c2ccccc12)NC(=O)OCc1cc2ccccc2o1)c1ccccc1

InChI Key InChIKey=IVIQHHCTWSXXCT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101416   

TargetSubstance-P receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50101416([2-(1H-Indol-3-yl)-1-methyl-1-(1-phenyl-ethylcarba...)
Affinity DataIC50: 1.05nMAssay Description:Inhibition of specific binding at tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50101416([2-(1H-Indol-3-yl)-1-methyl-1-(1-phenyl-ethylcarba...)
Affinity DataIC50: 5.90nMAssay Description:In vitro affinity for specific binding at Gerbil tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50101416([2-(1H-Indol-3-yl)-1-methyl-1-(1-phenyl-ethylcarba...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50101416([2-(1H-Indol-3-yl)-1-methyl-1-(1-phenyl-ethylcarba...)
Affinity DataIC50: 0.550nMAssay Description:Binding affinity towards tachykinin receptor 1 in human IM9 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed