BDBM50101263 CHEMBL49040::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(4-methoxy-phenyl)-1,3-dihydro-isoindol-2-yl]-acetic acid

SMILES CCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1ccc(OC)cc1)c1ccc2OCOc2c1

InChI Key InChIKey=RAMHCNBQMDDFCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50101263   

TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50101263([(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(4-met...)
Affinity DataIC50: 96nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50101263([(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(4-met...)
Affinity DataIC50: 96nMAssay Description:Ability to displace [125I]ET1 from the rat endothelin A receptor expressed in rat aorta smooth muscle cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed