BDBM50101164 CHEMBL295152::N-{4-[4-(2-{2-(3,5-Dimethyl-phenyl)-5-[2-(2,5-dimethyl-pyrrolidin-1-yl)-1,1-dimethyl-2-oxo-ethyl]-1H-indol-3-yl}-ethylamino)-butyl]-phenyl}-methanesulfonamide

SMILES CC1CCC(C)N1C(=O)C(C)(C)c1ccc2[nH]c(c(CCNCCCCc3ccc(NS(C)(=O)=O)cc3)c2c1)-c1cc(C)cc(C)c1

InChI Key InChIKey=CERGKSWDFXQEKG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101164   

TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50101164(N-{4-[4-(2-{2-(3,5-Dimethyl-phenyl)-5-[2-(2,5-dime...)
Affinity DataIC50: 3nMAssay Description:Inhibition of [125I]buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the absence of bovine serum albumin (BSA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50101164(N-{4-[4-(2-{2-(3,5-Dimethyl-phenyl)-5-[2-(2,5-dime...)
Affinity DataIC50: 65nMAssay Description:Inhibition GnRH-stimulated luteinizing hormone (LH) release from rat pituitary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50101164(N-{4-[4-(2-{2-(3,5-Dimethyl-phenyl)-5-[2-(2,5-dime...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the presence of 0.1% bovine serum albumin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed