BDBM50101090 CHEMBL3326222

SMILES Cl.Cl.CN(C)[C@]1(CC[C@@H](CC1)NCCc1c[nH]c2ccccc12)c1ccccc1

InChI Key InChIKey=ZDSRRNGYNZJQML-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101090   

TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101090(CHEMBL3326222)
Affinity DataEC50:  5.10E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO-K1 cells assessed as stimulation of [35S]-GTPgammaS binding by scintillation proximity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101090(CHEMBL3326222)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at human NOP receptor expressed in CHO-K1 cells assessed as stimulation of [35S]-GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101090(CHEMBL3326222)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101090(CHEMBL3326222)
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed