BDBM50101003 3-((3-ethoxybenzyl)(3-phenoxyphenyl)amino)-1,1,1-trifluoropropan-2-ol::3-[(3-Ethoxy-benzyl)-(3-phenoxy-phenyl)-amino]-1,1,1-trifluoro-propan-2-ol::CHEMBL416623

SMILES CCOc1cccc(CN(CC(O)C(F)(F)F)c2cccc(Oc3ccccc3)c2)c1

InChI Key InChIKey=HRWJIDJGKLAPHP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50101003   

TargetCholesteryl ester transfer protein(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101003(3-((3-ethoxybenzyl)(3-phenoxyphenyl)amino)-1,1,1-t...)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro human CETP inhibitory activity assessed by measuring the rate of [3H]cholesteryl ester ([3H]CE) from HDL donor particles to LDL acceptor par...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101003(3-((3-ethoxybenzyl)(3-phenoxyphenyl)amino)-1,1,1-t...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of cholesteryl ester transfer protein in presence of human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101003(3-((3-ethoxybenzyl)(3-phenoxyphenyl)amino)-1,1,1-t...)
Affinity DataIC50: 1.60E+3nMAssay Description:Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101003(3-((3-ethoxybenzyl)(3-phenoxyphenyl)amino)-1,1,1-t...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CETPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101003(3-((3-ethoxybenzyl)(3-phenoxyphenyl)amino)-1,1,1-t...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human CETP in buffer assessed as transfer of [3H]-cholesteryl ester from HDL donor particles to LDL acceptor particlesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Rabbit)
Al-Zaytoonah Private University of Jordan

Curated by ChEMBL
LigandPNGBDBM50101003(3-((3-ethoxybenzyl)(3-phenoxyphenyl)amino)-1,1,1-t...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed