BDBM50100954 5-Trifluoromethyl-1,2,3,4-tetrahydro-1,4-methano-naphthalen-9-ylamine::CHEMBL35982

SMILES c1cc2c(c(c1)C(F)(F)F)[C@H]3CC[C@@H]2[C@@H]3N

InChI Key InChIKey=HHIJEPNAHYLKPE-UHFFFAOYSA-N

Data  6 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50100954   

TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50100954(5-Trifluoromethyl-1,2,3,4-tetrahydro-1,4-methano-n...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibitory constant against human phenylethanolamine N-methyl-transferase over-expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50100954(5-Trifluoromethyl-1,2,3,4-tetrahydro-1,4-methano-n...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibitory constant against bovine phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50100954(5-Trifluoromethyl-1,2,3,4-tetrahydro-1,4-methano-n...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibitory constant against bovine phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50100954(5-Trifluoromethyl-1,2,3,4-tetrahydro-1,4-methano-n...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibitory constant against bovine phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50100954(5-Trifluoromethyl-1,2,3,4-tetrahydro-1,4-methano-n...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibitory constant against human phenylethanolamine N-methyl-transferase over-expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50100954(5-Trifluoromethyl-1,2,3,4-tetrahydro-1,4-methano-n...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibitory constant against human phenylethanolamine N-methyl-transferase over-expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)