BDBM50100754 Ac-Phe-Arg-Trp-NH2::CHEMBL441988

SMILES CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

InChI Key InChIKey=LUCUFURZWPZEOH-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50100754   

TargetMelanocortin receptor 3(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50100754(Ac-Phe-Arg-Trp-NH2 | CHEMBL441988)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC3 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50100754(Ac-Phe-Arg-Trp-NH2 | CHEMBL441988)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC4 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50100754(Ac-Phe-Arg-Trp-NH2 | CHEMBL441988)
Affinity DataEC50:  36nMAssay Description:Agonist activity at mouse MC5 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50100754(Ac-Phe-Arg-Trp-NH2 | CHEMBL441988)
Affinity DataEC50: >1.00E+5nMAssay Description:Functional activity at the mouse melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50100754(Ac-Phe-Arg-Trp-NH2 | CHEMBL441988)
Affinity DataEC50: >1.00E+5nMAssay Description:Functional activity at the mouse melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50100754(Ac-Phe-Arg-Trp-NH2 | CHEMBL441988)
Affinity DataEC50:  5.87E+3nMAssay Description:Functional activity at the mouse melanocortin 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed