BDBM50100684 6,7-Dimethoxy-2-(4-methylamino-phenyl)-1-oxo-4-(3,4,5-trimethoxy-phenyl)-1,2-dihydro-isoquinoline-3-carboxylic acid methyl ester::CHEMBL305014

SMILES CNc1ccc(cc1)-n1c(C(=O)OC)c(-c2cc(OC)c(OC)c(OC)c2)c2cc(OC)c(OC)cc2c1=O

InChI Key InChIKey=AREIFZORRGASMW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100684   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Dog)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50100684(6,7-Dimethoxy-2-(4-methylamino-phenyl)-1-oxo-4-(3,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against canine lung Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50100684(6,7-Dimethoxy-2-(4-methylamino-phenyl)-1-oxo-4-(3,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against canine heart Phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50100684(6,7-Dimethoxy-2-(4-methylamino-phenyl)-1-oxo-4-(3,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed