BDBM50100663 CHEMBL542878::methyl 2-(4-aminophenyl)-4-(3-hydroxy-4,5-dimethoxyphenyl)-1-oxo-7-(2-pyridylmethoxy)-1,2-dihydro-3-isoquinolinecarboxylate.dihydrochloride

SMILES COC(=O)c1c(-c2cc(O)c(OC)c(OC)c2)c2ccc(OCc3ccccn3)cc2c(=O)n1-c1ccc(N)cc1

InChI Key InChIKey=HQKDKMHMRDUWAC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100663   

LigandPNGBDBM50100663(methyl 2-(4-aminophenyl)-4-(3-hydroxy-4,5-dimethox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Dog)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50100663(methyl 2-(4-aminophenyl)-4-(3-hydroxy-4,5-dimethox...)
Affinity DataIC50: 8.5nMAssay Description:Inhibitory activity against canine lung Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50100663(methyl 2-(4-aminophenyl)-4-(3-hydroxy-4,5-dimethox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against canine heart Phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed