BDBM50100583 7-(4-Dimethylamino-phenyl)-6-(4-methoxy-phenyl)-pyrido[2,3-d]pyrimidin-4-ylamine::CHEMBL302938

SMILES COc1ccc(cc1)-c1cc2c(N)ncnc2nc1-c1ccc(cc1)N(C)C

InChI Key InChIKey=ZADGRKLNRFXWQT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50100583   

TargetAdenosine kinase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100583(7-(4-Dimethylamino-phenyl)-6-(4-methoxy-phenyl)-py...)
Affinity DataIC50: 91.7nMAssay Description:In vitro inhibition of Adenosine kinase (AK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100583(7-(4-Dimethylamino-phenyl)-6-(4-methoxy-phenyl)-py...)
Affinity DataIC50: 567nMAssay Description:Inhibition of adenosine phosphorylation in confluent IMR-32 (human neuroblastoma) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100583(7-(4-Dimethylamino-phenyl)-6-(4-methoxy-phenyl)-py...)
Affinity DataIC50: 567nMAssay Description:Inhibitory concentration against Adenosine Kinase (intact cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100583(7-(4-Dimethylamino-phenyl)-6-(4-methoxy-phenyl)-py...)
Affinity DataIC50: 92nMAssay Description:Inhibitory concentration against Adenosine Kinase (enzyme)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed