BDBM50100468 CHEMBL291418::N-(4-Hydroxy-5-hydroxymethyl-2-{6-[(naphthalen-2-ylmethyl)-amino]-purin-9-ylmethyl}-tetrahydro-furan-3-yl)-3-methoxy-benzamide

SMILES COc1cccc(c1)C(=O)N[C@@H]1C(Cn2cnc3c(NCc4ccc5ccccc5c4)ncnc23)OC(CO)[C@@H]1O

InChI Key InChIKey=YAVYSJYLRJLWJO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50100468   

TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50100468(N-(4-Hydroxy-5-hydroxymethyl-2-{6-[(naphthalen-2-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of Trypanosoma cruzi GAPDH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase, cytosolic(Leishmania mexicana)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50100468(N-(4-Hydroxy-5-hydroxymethyl-2-{6-[(naphthalen-2-y...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against Leishmania mexicana GAPDHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50100468(N-(4-Hydroxy-5-hydroxymethyl-2-{6-[(naphthalen-2-y...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of rabbit muscle GAPDH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50100468(N-(4-Hydroxy-5-hydroxymethyl-2-{6-[(naphthalen-2-y...)
Affinity DataIC50: 2.40E+4nMAssay Description:In vitro inhibition of Trypanosoma brucei GAPDH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed