BDBM50100467 3,5-Dichloro-N-(4-hydroxy-5-hydroxymethyl-2-{6-[(3-methoxy-naphthalen-1-ylmethyl)-amino]-9H-purin-3-ylmethyl}-tetrahydro-furan-3-yl)-benzamide::CHEMBL64311

SMILES COc1cc(CNc2ncnc3n(cnc23)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2NC(=O)c2cc(Cl)cc(Cl)c2)c2ccccc2c1

InChI Key InChIKey=VRFZSNJOQMAMEN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50100467   

TargetGlyceraldehyde-3-phosphate dehydrogenase, cytosolic(Leishmania mexicana)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50100467(3,5-Dichloro-N-(4-hydroxy-5-hydroxymethyl-2-{6-[(3...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against Leishmania mexicana GAPDHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50100467(3,5-Dichloro-N-(4-hydroxy-5-hydroxymethyl-2-{6-[(3...)
Affinity DataIC50: 4.50E+4nMAssay Description:In vitro inhibition of Trypanosoma brucei GAPDH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50100467(3,5-Dichloro-N-(4-hydroxy-5-hydroxymethyl-2-{6-[(3...)
Affinity DataIC50: 4.00E+4nMAssay Description:In vitro inhibition of Trypanosoma cruzi GAPDH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50100467(3,5-Dichloro-N-(4-hydroxy-5-hydroxymethyl-2-{6-[(3...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of rabbit muscle GAPDH.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed