BDBM50100341 (2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl-hexadeca-2,4,6,12-tetraenoic acid [(S)-1-hydroxymethyl-2-((1S,2S,6S)-2-hydroxy-3-oxo-7-oxa-bicyclo[4.1.0]hept-4-en-2-yl)-ethyl]-amide::CHEMBL418376

SMILES CC[C@@H](C)\C=C(/C)C[C@@H](C)C[C@@H](C)\C=C\C=C\C=C\C(=O)N[C@H](CO)C[C@]1(O)[C@H]2O[C@H]2C=CC1=O

InChI Key InChIKey=KSIWZCYBCSQXTA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50100341   

TargetSphingomyelin phosphodiesterase 2(Rat)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against neutral sphingomyelinase (N-Smase) from rat brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)
Affinity DataIC50: 4.93E+4nMAssay Description:Inhibitory concentration against neutral sphingomyelinase (N-Smase) from rat brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat brain microsomes nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed