BDBM50100307 2-(2-Biphenyl-4-yl-ethoxy)-4-imidazol-1-ylmethyl-benzonitrile::CHEMBL22547

SMILES N#Cc1ccc(Cn2ccnc2)cc1OCCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=ZMHFYICSWNADEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100307   

LigandPNGBDBM50100307(2-(2-Biphenyl-4-yl-ethoxy)-4-imidazol-1-ylmethyl-b...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50100307(2-(2-Biphenyl-4-yl-ethoxy)-4-imidazol-1-ylmethyl-b...)
Affinity DataIC50: 86nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed